Trial intelligence / Profile preview

Phase 2 basket study of zilovertamab vedotin alone or with nemtabrutinib in relapsed/refractory B-cell malignancies

MOH_2022-04-11_010707Phase 2Active, not recruiting

Sponsor
Merck & Co.
Start
Apr 2022
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label trial of zilovertamab vedotin and nemtabrutinib in B-cell malignancy, mantle cell lymphoma (MCL), Richter's syndrome (RS) and 2 more (8 cohorts), sponsored by Merck & Co. Started Apr 2022; status: active, not recruiting.

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Drugs

zilovertamab vedotinnemtabrutinib
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Conditions

B-cell malignancymantle cell lymphoma (MCL)Richter's syndrome (RS)follicular lymphoma (FL)chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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