Trial intelligence / Profile preview

IMPAHCT phase 2b/3 trial of inhaled AV-101 in pulmonary arterial hypertension

MOH_2022-11-10_012172Phase 3Completed

Sponsor
Aerovate Therapeutics
Start
Apr 2022
Modality
Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial of 4-chlorokynurenine and imatinib in pulmonary arterial hypertension (PAH) (6 arms), sponsored by Aerovate Therapeutics. Primary endpoints: Placebo-corrected change in pulmonary vascular resistance and Placebo-corrected change in 6-minute walk distance. Started Apr 2022; status: completed.

02

Drugs

4-chlorokynurenineimatinib
03

Conditions

pulmonary arterial hypertension (PAH)

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