Trial intelligence / Profile preview

Palbociclib with temozolomide + irinotecan versus temozolomide + irinotecan in relapsed or refractory Ewing sarcoma

MOH_2023-04-18_010448Phase 2Not yet recruiting

Sponsor
Pfizer
Start
Mar 2023
Modality
Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in Ewing sarcoma comparing Palbociclib in combination with temozolomide and irinotecan with Temozolomide and irinotecan alone (2 arms). Primary endpoint: Efficacy comparison of palbociclib + temozolomide + irinotecan versus temozolomide + irinotecan. Planned start Mar 2023; status: not yet recruiting.

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Drugs

palbociclibtemozolomideirinotecan
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Conditions

Ewing sarcoma

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