Trial intelligence / Profile preview

VERITAC-2: ARV-471 versus fulvestrant in ER-positive, HER2-negative advanced breast cancer

MOH_2023-04-27_012530Phase 3Not yet recruiting

Sponsor
Pfizer
Start
Dec 2022
Modality
Small Molecules, PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in breast cancer comparing ARV-471 with fulvestrant (2 arms). Primary endpoint: Progression-free survival. Planned start Dec 2022; status: not yet recruiting.

02

Drugs

vepdegestrantfulvestrant
03

Conditions

breast cancer

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