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Domvanalimab + zimberelimab plus chemotherapy versus nivolumab plus chemotherapy for first-line unresectable or metastatic upper gastrointestinal adenocarcinoma

MOH_2023-04-30_012590Phase 3Recruiting

Sponsor
Arcus Biosciences
Start
Mar 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial of domvanalimab and zimberelimab in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma, esophageal adenocarcinoma (EAC) and 1 more (2 arms), sponsored by Arcus Biosciences. Primary endpoint: Overall survival. Started Mar 2023; status: recruiting.

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Drugs

domvanalimabzimberelimab
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)upper gastrointestinal adenocarcinoma

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