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Phase 1/2 study of ubamatamab alone or with cemiplimab in recurrent ovarian and related MUC16-positive cancers

MOH_2023-06-29_012319Phase 2Recruiting

Sponsor
Regeneron Pharmaceuticals
Start
Feb 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of ubamatamab, cemiplimab and sarilumab in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) (3 cohorts), sponsored by Regeneron Pharmaceuticals. Primary endpoints: Objective response rate by RECIST 1.1, Safety profile and 1 more. Started Feb 2023; status: recruiting.

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Drugs

ubamatamabcemiplimabsarilumab
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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