Trial intelligence / Profile preview

Phase 3 randomized study of teclistamab or talquetamab with daratumumab and lenalidomide versus DRd in newly diagnosed transplant-ineligible multiple myeloma

MOH_2024-01-03_013156Phase 3Recruiting

Sponsor
Janssen Pharmaceutical
Start
Dec 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised trial of teclistamab, talquetamab, daratumumab, lenalidomide and dexamethasone in multiple myeloma (MM) (3 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Response and survival-related efficacy assessment and Sustained MRD-negative complete response. Started Dec 2023; status: recruiting.

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Drugs

teclistamabtalquetamabdaratumumablenalidomidedexamethasone
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Conditions

multiple myeloma (MM)

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