Trial intelligence / Profile preview

Phase 3 study of sonrotoclax + zanubrutinib versus venetoclax + obinutuzumab in previously untreated chronic lymphocytic leukemia

MOH_2024-03-14_013315Phase 3Recruiting

Sponsor
BeiGene
Start
Mar 2024
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) comparing Sonrotoclax + zanubrutinib with Venetoclax + obinutuzumab (2 arms). Primary endpoint: Progression-free survival. Started Mar 2024; status: recruiting.

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Drugs

sonrotoclaxzanubrutinibvenetoclaxobinutuzumab
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Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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