Trial intelligence / Profile preview

Phase 3 adjuvant pembrolizumab with or without MK-2870 in resectable NSCLC without pCR after neoadjuvant pembrolizumab plus platinum-doublet chemotherapy and surgery

MOH_2024-03-26_013152Phase 3Recruiting

Sponsor
Merck & Co.
Start
Mar 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Adjuvant pembrolizumab + MK-2870 with Adjuvant pembrolizumab monotherapy (2 arms). Primary endpoint: Disease-free survival. Started Mar 2024; status: recruiting.

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Drugs

sacituzumab tirumotecanpembrolizumab
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Conditions

non-small cell lung cancer (NSCLC)

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