Trial intelligence / Profile preview

Phase 3 trial of MK-2870 + pembrolizumab versus physician's choice adjuvant therapy in residual TNBC after neoadjuvant pembrolizumab-based chemotherapy

MOH_2024-05-26_013433Phase 3Not yet recruiting

Sponsor
Merck & Co.
Start
May 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
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Overview

Phase 3, randomised, open-label trial of sacituzumab tirumotecan and pembrolizumab in triple-negative breast cancer (TNBC) (2 arms), sponsored by Merck & Co. Primary endpoint: Invasive disease-free survival. Planned start May 2024; status: not yet recruiting.

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Drugs

sacituzumab tirumotecanpembrolizumab
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Conditions

triple-negative breast cancer (TNBC)

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