Trial intelligence / Profile preview

KEYMAKER-U04 sub-study 04C of MK-2870 + enfortumab vedotin with or without pembrolizumab in advanced urothelial carcinoma

MOH_2024-07-25_013485Phase 2Active, not recruiting

Sponsor
Merck & Co.
Start
Jun 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial of sacituzumab tirumotecan, enfortumab vedotin and pembrolizumab in transitional cell carcinoma (TCC) (3 arms), sponsored by Merck & Co. Primary endpoints: Safety and tolerability and Pharmacokinetics. Started Jun 2024; status: active, not recruiting.

02

Drugs

sacituzumab tirumotecanenfortumab vedotinpembrolizumab
03

Conditions

transitional cell carcinoma (TCC)

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