Trial intelligence / Profile preview

DeLLphi-305: tarlatamab plus durvalumab versus durvalumab alone after first-line platinum-etoposide-durvalumab in extensive-stage small cell lung cancer

MOH_2024-08-12_013578Phase 3Active, not recruiting

Sponsor
Amgen
Start
Aug 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, open-label trial in small cell lung cancer (SCLC) comparing Tarlatamab + durvalumab with Durvalumab alone (2 arms). Primary endpoint: Overall survival. Started Aug 2024; status: active, not recruiting.

02

Drugs

tarlatamabdurvalumab
03

Conditions

small cell lung cancer (SCLC)

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