Trial intelligence / Profile preview

Izalontamab brengitecan versus physician's choice chemotherapy in previously untreated advanced triple-negative or ER-low/HER2-negative breast cancer not eligible for PD-(L)1 therapy

MOH_2025-08-25_014296Phase 3Recruiting

Sponsor
Bristol Myers Squibb
Start
May 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, open-label trial of izalontamab brengitecan in breast cancer and triple-negative breast cancer (TNBC) (3 arms), sponsored by Bristol Myers Squibb. Started May 2025; status: recruiting.

02

Drugs

izalontamab brengitecan
03

Conditions

breast cancertriple-negative breast cancer (TNBC)

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