Trial intelligence / Profile preview

Phase 3 trial of BGB-16673 versus pirtobrutinib in relapsed/refractory CLL or SLL after prior covalent BTK inhibitor

MOH_2025-11-09_015445Phase 3Recruiting

Sponsor
BeOne Medicines
Start
Oct 2025
Modality
Small Molecules, PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial of catadegbrutinib and pirtobrutinib in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) (2 arms), sponsored by BeOne Medicines. Started Oct 2025; status: recruiting.

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Drugs

catadegbrutinibpirtobrutinib
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Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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