Trial intelligence / Profile preview

Phase 2 open-label tumor-agnostic study of MK-1084 alone or with cetuximab in advanced KRAS G12C-mutated solid tumors

MOH_2025-11-09_015448Phase 2Recruiting

Sponsor
Merck & Co.
Start
Nov 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of calderasib and cetuximab in Nonhematologic neoplasms (2 arms), sponsored by Merck & Co. Primary endpoints: Safety of MK-1084, Efficacy of MK-1084 with or without cetuximab and 1 more. Started Nov 2025; status: recruiting.

02

Drugs

calderasibcetuximab
03

Conditions

Nonhematologic neoplasms

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