Trial intelligence / Profile preview

Phase 2 randomized double-blind placebo-controlled study of PRX-115 with or without methotrexate in adults with gout

MOH_2025-11-11_015452Phase 2Recruiting

Sponsor
Protalix BioTherapeutics
Start
Oct 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of prx-115 and methotrexate in gout (6 arms), sponsored by Protalix BioTherapeutics. Primary endpoint: Reduction of serum urate during month 6. Started Oct 2025; status: recruiting.

02

Drugs

prx-115methotrexate
03

Conditions

gout

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