Trial intelligence / Profile preview

Phase 3 study of sacituzumab tirumotecan plus pembrolizumab with or without bevacizumab versus standard maintenance therapy in first-line persistent, recurrent, or metastatic PD-L1-positive cervical cancer

MOH_2025-11-17_015470Phase 3Recruiting

Sponsor
Merck & Co.
Start
Nov 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial of sacituzumab tirumotecan, pembrolizumab and bevacizumab in Cervical Cancer (CC) (3 arms), sponsored by Merck & Co. Primary endpoint: Progression-free survival. Started Nov 2025; status: recruiting.

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Drugs

sacituzumab tirumotecanpembrolizumabbevacizumab
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Conditions

Cervical Cancer (CC)

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