Trial intelligence / Profile preview

Phase 3 randomized open-label study of GSK5764227 versus topotecan in relapsed small cell lung cancer

MOH_2025-11-19_015474Phase 3Recruiting

Sponsor
GSK
Start
Oct 2025
Modality
Small Molecules, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial of risvutatug rezetecan and topotecan in small cell lung cancer (SCLC) (2 arms), sponsored by GSK. Primary endpoints: Antitumor activity and Overall survival. Started Oct 2025; status: recruiting.

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Drugs

risvutatug rezetecantopotecan
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Conditions

small cell lung cancer (SCLC)

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