Trial intelligence / Profile preview

Phase 3 trial of PF-08634404 plus chemotherapy versus pembrolizumab plus chemotherapy in first-line advanced or metastatic non-small cell lung cancer

MOH_2025-11-26_015496Phase 3Recruiting

Sponsor
Pfizer
Start
Nov 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial of PF-08634404, pembrolizumab, carboplatin, paclitaxel and pemetrexed in non-small cell lung cancer (NSCLC) (4 arms), sponsored by Pfizer. Started Nov 2025; status: recruiting.

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Drugs

PF-08634404pembrolizumabcarboplatinpaclitaxelpemetrexed
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Conditions

non-small cell lung cancer (NSCLC)

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