Trial intelligence / Profile preview

TREVI-OC-01: Phase 3 AZD5335 versus mirvetuximab soravtansine or investigator's choice chemotherapy in platinum-resistant ovarian cancer

MOH_2025-11-30_015507Phase 3Not yet recruiting

Sponsor
AstraZeneca
Start
Nov 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of AZD5335 in ovarian cancer, primary peritoneal cancer (PPC) and fallopian tube cancer (PFTC) (4 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival. Planned start Nov 2025; status: not yet recruiting.

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Drugs

AZD5335
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Conditions

ovarian cancerprimary peritoneal cancer (PPC)fallopian tube cancer (PFTC)

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