Trial intelligence / Profile preview

LITESPARK-034: belzutifan + zanzalintinib versus belzutifan + placebo in previously treated advanced clear cell renal cell carcinoma

MOH_2026-02-25_015690Phase 3Not yet recruiting

Sponsor
Merck & Co.
Start
Feb 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in renal cell carcinoma (RCC) comparing WELIREG + zanzalintinib with WELIREG + placebo (2 arms). Planned start Feb 2026; status: not yet recruiting.

02

Drugs

belzutifanzanzalintinib
03

Conditions

renal cell carcinoma (RCC)

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