Trial intelligence / Profile preview

SIL204-SL plus standard chemotherapy versus standard chemotherapy alone for unresectable locally advanced pancreatic cancer with KRAS mutation

MOH_2026-04-16_015772Phase 2Not yet recruiting

Sponsor
Silexion Therapeutics
Start
Mar 2026
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial of SIL204-SL in pancreatic adenocarcinoma (PDAC) (4 arms), sponsored by Silexion Therapeutics. Planned start Mar 2026; status: not yet recruiting.

02

Drugs

SIL204-SL
03

Conditions

pancreatic adenocarcinoma (PDAC)

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