Trial intelligence / Profile preview

SHASTA-5 phase 3 study of plozasiran in adults with severe hypertriglyceridemia at high risk for acute pancreatitis

MOH_2026-05-17_015823Phase 3Recruiting

Sponsor
Arrowhead Pharmaceuticals
Start
Feb 2026
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in hypertriglyceridemia comparing Redemplo with Placebo (2 arms). Started Feb 2026; status: recruiting.

02

Drugs

plozasiran
03

Conditions

hypertriglyceridemia

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