Trial intelligence / Profile preview

Phase 2 open-label multicenter study of MK-1045 in relapsed/refractory CLL/SLL and Ph-negative B-ALL

MOH_2026-06-07_016867Phase 2Not yet recruiting

Sponsor
Merck & Co.
Start
May 2026
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of CN201 in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and B cell acute lymphoblastic leukemia (B-ALL) (2 cohorts), sponsored by Merck & Co. Primary endpoints: Safety and tolerability and Recommended dose for expansion. Planned start May 2026; status: not yet recruiting.

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Drugs

CN201
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Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)B cell acute lymphoblastic leukemia (B-ALL)

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