Trial intelligence / Profile preview

Phase 2 randomized open-label active-controlled study of SRSD107 versus enoxaparin for venous thromboembolism prevention after total knee arthroplasty

MOH_2026-07-18_016941Phase 2Not yet recruiting

Sponsor
Sirius Therapeutics
Start
May 2026
Modality
Recombinant Proteins and Enzymes, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of SRSD107 and enoxaparin in venous thromboembolism (VTE) (4 arms), sponsored by Sirius Therapeutics. Primary endpoints: Efficacy of SRSD107 versus enoxaparin and Safety of SRSD107 versus enoxaparin. Planned start May 2026; status: not yet recruiting.

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Drugs

SRSD107enoxaparin
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Conditions

venous thromboembolism (VTE)

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