Trial intelligence / Profile preview

Phase 3 REJOICE-Ovarian trial of raludotatug deruxtecan maintenance with or without bevacizumab versus standard maintenance in newly diagnosed advanced non-HRD-positive ovarian cancer

MOH_2026-07-22_016949Phase 3Not yet recruiting

Sponsor
Merck & Co.
Start
Jul 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of raludotatug deruxtecan and bevacizumab in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) (2 arms), sponsored by Merck & Co. Primary endpoint: Progression-free survival. Planned start Jul 2026; status: not yet recruiting.

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Drugs

raludotatug deruxtecanbevacizumab
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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