Trial intelligence / Profile preview

LUMINA IgAN: zigakibart + atrasentan versus zigakibart + placebo in primary IgA nephropathy

MOH_2026-08-25_017005Phase 3Not yet recruiting

Sponsor
Novartis
Start
Aug 2026
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, double-blind trial in IgA nephropathy (IgAN) comparing zigakibart + atrasentan with zigakibart + placebo (2 arms). Primary endpoints: Reduction in proteinuria and Delay of disease progression. Planned start Aug 2026; status: not yet recruiting.

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Drugs

zigakibartatrasentan
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Conditions

IgA nephropathy (IgAN)

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