Trial intelligence / Profile preview

Open-label phase 1/2 single-arm study of Promitil with radiotherapy in cisplatin-ineligible head and neck cancer

MOH_2026-09-09_017027Phase 2Recruiting

Sponsor
מחקר חוקר יזם
Start
Mar 2026
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
1
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Overview

Phase 2, open-label trial of Mitomycin-c lipidic prodrug in head and neck squamous cell carcinoma (HNSCC), sponsored by מחקר חוקר יזם. Primary endpoints: Short-term safety of Promitil with radiotherapy, Safe dose determination and 1 more. Started Mar 2026; status: recruiting.

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Drugs

Mitomycin-c lipidic prodrug
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Conditions

head and neck squamous cell carcinoma (HNSCC)

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