Trial intelligence / Profile preview

Phase 3 trial of amivantamab after definitive concurrent platinum-based chemoradiotherapy for unresectable locally advanced head and neck squamous cell carcinoma

MOH_2026-10-07_017067Phase 3Not yet recruiting

Sponsor
Janssen Pharmaceutical
Start
Oct 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial in head and neck squamous cell carcinoma (HNSCC) comparing Amivantamab with Observation (standard of care) (2 arms). Primary endpoint: Event-free survival. Planned start Oct 2026; status: not yet recruiting.

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Drugs

amivantamab
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Conditions

head and neck squamous cell carcinoma (HNSCC)

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