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Arterial Disease Multifactorial Intervention Trial
NCT00000539Phase 3Completed
- Sponsor
- National Heart, Lung, and Blood Institute
- Start
- Sep 1992
- Modality
- Orthosteric Ligands, Metabolically Activated Prodrugs
01
Overview
Phase 3, randomised trial of niacin, beta-carotene, vitamin e, ascorbic acid and warfarin in Peripheral Arterial Disease (PAD) (4 arms), sponsored by National Heart, Lung, and Blood Institute. Primary endpoint: Efficacy and safety of HDL-C raising, antioxidant therapy, antithrombotic therapy, and their combinations at 1 year. Started Sep 1992; status: completed.
02
Drugs
niacinbeta-carotenevitamin eascorbic acidwarfarin
03
Conditions
Peripheral Arterial Disease (PAD)
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