Trial intelligence / Profile preview

Dose Intensive Chemotherapy for Children with Malignant Brain Tumors (Head Start II)

NCT00003273Phase 2Withdrawn

Sponsor
NYU Langone Health
Start
Nov 1997
Modality
DNA Intercalators/Alkylators, Orthosteric Ligands, Covalent Small Molecules
Countries
3
01

Overview

Phase 2, open-label trial of thiotepa, etoposide, carboplatin, cisplatin, vincristine and 3 more in brain tumor, medulloblastoma, primitive neuroectodermal tumor (PNET) and 7 more (3 arms), sponsored by NYU Langone Health. Primary endpoints: Toxicity of Induction Chemotherapy and Response Rate to Induction Chemotherapy. Planned start Nov 1997; status: withdrawn.

02

Drugs

thiotepaetoposidecarboplatincisplatinvincristine
03

Conditions

brain tumormedulloblastomaprimitive neuroectodermal tumor (PNET)ependymomaglioblastoma (GBM)

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