Trial intelligence / Profile preview

Capsaicin for Preemptive Analgesia in Third Molar Extraction

NCT00088686Phase 2

Key facts

Status
Completed
Start
Jul 2004
Countries
1
Sponsor
National Institute of Dental and Craniofacial Research
Modality
Small Molecules
Conditions
postoperative pain
01

Overview

Phase 2, randomised, double-blind trial of capsaicin in postoperative pain (3 arms), sponsored by National Institute of Dental and Craniofacial Research. Primary endpoints: Pain Ratings at 6 hours and Time to Analgesic Rescue Medication Request at 6 hours. Started Jul 2004; status: completed.

02

Design

3 arms
Study design
RandomizedDouble-blind
  • Capsaicin

    Intramucosal Capsaicin + IV Placebo

  • Ketorolac

    Intramucosal Placebo + IV Ketorolac

  • Placebo

    Intramucosal Placebo + IV Placebo

03

Endpoints

Primary

  • Pain Ratings

  • Time to Analgesic Rescue Medication Request

Secondary

  • Analgesic Use

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