Trial intelligence / Profile preview

Stem Cell Transplant for High Risk Hemoglobinopathy

NCT00176852Phase 3Completed

Sponsor
Masonic Cancer Center
Start
Jun 2002
Primary completion
Mar 2014
Modality
Monoclonal Antibodies
Countries
1
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Overview

Phase 3, open-label trial of alemtuzumab in sickle cell disease (SCD), thalassemia, severe congenital neutropenia (SCN) and 2 more (2 arms), sponsored by Masonic Cancer Center. Primary endpoint: Number of Patients Who Experienced Grade 3-5 Treatment Related Toxicity at 1 year. Started Jun 2002; status: completed.

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Drugs

alemtuzumab
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Conditions

sickle cell disease (SCD)thalassemiasevere congenital neutropenia (SCN)Diamond-Blackfan anemia (DBA)Shwachman-Diamond syndrome (SDS)

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