Trial intelligence / Profile preview

Gemcitabine and Pemetrexed in Primary Unknown Adenocarcinoma

NCT00191503Phase 2

Key facts

Status
Completed
Start
Jan 2005
Countries
1
Modality
Small Molecules
Conditions
Adenocarcinoma
01

Overview

Phase 2, open-label, single-arm trial of pemetrexed and gemcitabine in Adenocarcinoma, sponsored by Eli Lilly and Company. Primary endpoint: Objective Response Rate. Started Jan 2005; status: completed.

02

Design

1 arm
Study design
Non-randomizedOpen-labelSingle group
  • Pemetrexed + Gemcitabine

    Combination chemotherapy with Pemetrexed and Gemcitabine

03

Who it enrols

Patients with histologically proven adenocarcinoma of unknown origin with predominant liver metastases, ECOG 0-1, and adequate organ function.

04

Endpoints

Primary

  • Objective Response Rate

Secondary

  • Overall Survival

  • Toxicities of Therapy

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