Trial intelligence / Profile preview

Escitalopram in Obsessive-compulsive Disorder

NCT00215137Phase 2

Key facts

Status
Completed
Start
Oct 2004
Primary completion
Jan 2009
Countries
1
Sponsor
Duke University
Modality
Small Molecules
Conditions
obsessive compulsive disorder (OCD)
01

Overview

Phase 2, randomised, double-blind trial of escitalopram in obsessive compulsive disorder (OCD) (3 arms), sponsored by Duke University. Primary endpoint: Yale Brown Obsessive Compulsive Scale at Week 8. Started Oct 2004; status: completed.

02

Design

3 arms
Study design
RandomizedDouble-blind
  • Open Label Escitalopram

    Daily escitalopram 10-20 mg

  • Placebo

    Placebo comparator

  • Escitalopram

    Continued escitalopram 20 mg

03

Who it enrols

Patients with OCD and a YBOCS score >= 16, excluding those with other primary psychiatric disorders, substance abuse, or prior failure of citalopram/escitalopram.

04

Endpoints

Primary

  • Yale Brown Obsessive Compulsive Scale

05

Results

Primary endpoints met

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