Trial intelligence / Profile preview

Lamotrigine for Neuroprotection in Secondary Progressive MS

NCT00257855Phase 2Completed

Sponsor
UCLH
Start
Nov 2005
Primary completion
Jan 2009
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in secondary-progressive multiple sclerosis (SPMS) comparing Lamotrigine with Placebo (2 arms). Primary endpoint: Change in central brain volume on MRI using the 'Loseff method' at 24 months. Started Nov 2005; status: completed.

02

Drugs

lamotrigine
03

Conditions

secondary-progressive multiple sclerosis (SPMS)

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