Trial intelligence / Profile preview

HIT-2000 Therapy Optimization Study

NCT00303810Phase 3Completed

Sponsor
University Medical Center Hamburg-Eppendorf
Start
Jan 2001
Primary completion
Dec 2013
Modality
DNA Intercalators/Alkylators, Orthosteric Ligands, Covalent Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of carboplatin, cisplatin, cyclophosphamide, etoposide, lomustine and 3 more in medulloblastoma, supratentorial primitive neuroectodermal tumor (sPNET) and ependymoma (7 arms), sponsored by University Medical Center Hamburg-Eppendorf. Primary endpoints: Event-Free Survival at 5 years and Overall Survival at 5 years. Started Jan 2001; status: completed.

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Drugs

carboplatincisplatincyclophosphamideetoposidelomustine
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Conditions

medulloblastomasupratentorial primitive neuroectodermal tumor (sPNET)ependymoma

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