Trial intelligence / Profile preview

Bevacizumab Plus Irinotecan in Pediatric Recurrent Brain Tumors

NCT00381797Phase 2Completed

Sponsor
National Cancer Institute
Start
Aug 2006
Primary completion
Oct 2015
Modality
Monoclonal Antibodies
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of bevacizumab in malignant glioma, diffuse intrinsic brainstem glioma (DIPG), medulloblastoma and 2 more, sponsored by National Cancer Institute. Primary endpoints: Objective Response Rate Sustained for >= 8 Weeks at 24 weeks and Sustained Disease Stabilization Rate at 24 weeks. Started Aug 2006; status: completed.

02

Drugs

bevacizumab
03

Conditions

malignant gliomadiffuse intrinsic brainstem glioma (DIPG)medulloblastomaependymomalow-grade glioma (LGG)

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