Trial intelligence / Profile preview

Risk-Adapted Therapy for Young Children With Brain Tumors

NCT00602667Phase 2Active, not recruiting

Sponsor
St. Jude Children's Research Hospital
Start
Dec 2007
Primary completion
Sep 2017
Modality
Orthosteric Ligands
Countries
2
01

Overview

Phase 2, open-label trial of methotrexate in central nervous system tumor, medulloblastoma, primitive neuroectodermal tumor (PNET) and 5 more (3 arms), sponsored by St. Jude Children's Research Hospital. Primary endpoints: Progression-free Survival at 1 year, Progression-free Survival by DNA Methylation Subgroup at 1 year and 1 more. Started Dec 2007; status: active, not recruiting.

02

Drugs

methotrexate
03

Conditions

central nervous system tumormedulloblastomaprimitive neuroectodermal tumor (PNET)pineoblastoma (PB)Atypical teratoid rhabdoid tumor (ATRT)

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