Trial intelligence / Profile preview

DC Vaccine +/- Cyclophosphamide in Stage IV Melanoma

NCT00722098Phase 2

Key facts

Status
Terminated
Start
Jun 2008
Primary completion
Apr 2011
Countries
1
Sponsor
Baylor Scott & White Research Institute
Modality
Whole Cell Cancer Vaccines, Dendritic Cell Vaccines
Conditions
Malignant Melanoma (MM)
01

Overview

Phase 2, randomised, double-blind trial of Dendritic cell vaccine (Mackay Memorial Hospital) in Malignant Melanoma (MM), sponsored by Baylor Scott & White Research Institute. Started Jun 2008; status: terminated.

02

Design

Study design
RandomizedDouble-blind
03

Who it enrols

HLA-A*0201 positive patients with Stage IV melanoma, ECOG 0-1, and no active CNS disease.

04

Registry description

The purpose of this study is to determine whether the combination of chemotherapy (Cyclophosphamide) and CD34-DC vaccines results in the improved rate of clinical responses for stage IV melanoma patients.

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