Trial intelligence / Profile preview

URTH: Reduced Intensity Conditioning HCT for Thalassemia

NCT01005576Phase 2Completed

Sponsor
Washington University School of Medicine
Start
Jan 2010
Primary completion
Apr 2014
Modality
Monoclonal Antibodies, Orthosteric Ligands, Metabolically Activated Prodrugs
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of alemtuzumab, fludarabine, melphalan, thiotepa and hydroxyurea in beta thalassemia major, sponsored by Washington University School of Medicine. Primary endpoint: Event-free Survival at 1 year. Started Jan 2010; status: completed.

02

Drugs

alemtuzumabfludarabinemelphalanthiotepahydroxyurea
03

Conditions

beta thalassemia major

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