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Hybrid ImmunoTherapy (ATG/Dexamethasone/Etoposide) for Hemophagocytic LymphoHistiocytosis

NCT01104025Phase 2Completed

Sponsor
Cincinnati Children's Hospital Medical Center
Start
Apr 2010
Primary completion
Nov 2015
Modality
Recombinant Proteins and Enzymes, Orthosteric Ligands, Antibody-Based Therapeutics
Countries
2
01

Overview

Phase 2, open-label, single-arm trial of antithymocyte globulin rabbit, dexamethasone and etoposide in hemophagocytic lymphohistiocytosis (HLH), sponsored by Cincinnati Children's Hospital Medical Center. Primary endpoint: Overall Survival at 8 weeks. Started Apr 2010; status: completed.

02

Drugs

antithymocyte globulin rabbitdexamethasoneetoposide
03

Conditions

hemophagocytic lymphohistiocytosis (HLH)

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