Trial intelligence / Profile preview

MK-2206 and Bicalutamide in Prostate Cancer with Rising PSA

NCT01251861Phase 2Completed

Sponsor
National Cancer Institute
Start
Mar 2011
Primary completion
Jul 2018
Modality
Small Molecules
Countries
2
01

Overview

Phase 2, randomised, open-label trial in prostate cancer (PCa) comparing Arm A (observation and bicalutamide) with Arm B (Akt inhibitor MK2206 and bicalutamide) (2 arms). Primary endpoint: Proportion of Patients With Undetectable PSA Level (< 0.2 ng/mL) at 44 weeks. Started Mar 2011; status: completed.

02

Drugs

MK-2206
03

Conditions

prostate cancer (PCa)

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