Trial intelligence / Profile preview

Methylene Blue + AS-AQ for Uncomplicated Falciparum Malaria in Children

NCT01407887Phase 2

Key facts

Status
Completed
Start
Aug 2011
Primary completion
Aug 2011
Countries
1
Sponsor
Heidelberg University
Modality
Small Molecules
Conditions
Malaria
01

Overview

Phase 2, randomised, open-label trial of methylene blue in Malaria (2 arms), sponsored by Heidelberg University. Primary endpoint: P. falciparum gametocyte prevalence at Day 14. Started Aug 2011; status: completed.

02

Design

2 arms
Study design
RandomizedOpen-label
  • AS-AQ-MB

    Artesunate + Amodiaquine + Methylene Blue

  • AS-AQ

    Artesunate + Amodiaquine

03

Endpoints

Primary

  • P. falciparum gametocyte prevalence

Secondary

  • P. falciparum gametocyte prevalence and density

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