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Simvastatin in choroideremia
NCT01654562Phase 2
Key facts
- Status
- Terminated
- Start
- Dec 2012
- Primary completion
- Jul 2013
- Countries
- 1
- Sponsor
- University of Alberta
- Modality
- Small Molecules
- Drugs
- simvastatin
- Conditions
- choroideremia
01
Overview
Phase 2, open-label trial of simvastatin in choroideremia, sponsored by University of Alberta. Primary endpoint: Full-field scotopic threshold at 10 weeks. Started Dec 2012; status: terminated.
02
Design
- Study design
- Non-randomizedOpen-label
03
Who it enrols
Males over 18 with choroideremia and healthy age-matched controls, excluding those already on statins.
04
Endpoints
Primary
Full-field scotopic threshold
Secondary
Microperimetry
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