Trial intelligence / Profile preview

hCE1m6-NSCs and Irinotecan for Recurrent High-Grade Gliomas

NCT02055196Phase 1Withdrawn

Sponsor
City of Hope
Primary completion
May 2014
Modality
Gene Editing, Gene Silencing, Stem Cell Therapies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of carboxylesterase-expressing allogeneic neural stem cells in glioma, sponsored by City of Hope. Primary endpoints: Incidence of dose-limiting toxicity at 6 weeks, Incidence of all attributable toxicities up to 15 years and 1 more. Status: withdrawn.

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Drugs

carboxylesterase-expressing allogeneic neural stem cells
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Conditions

glioma

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