Trial intelligence / Profile preview

Brain Kinetics of 11C-MK-3168 and JNJ-42165279 Occupancy

NCT02169973Phase 1Completed

Sponsor
Janssen Pharmaceutical
Start
Feb 2014
Primary completion
Jul 2014
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of JNJ-42165279 in Social Anxiety Disorder (SAD) and major depressive disorder (MDD) (3 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Compartmental Model of the Volume of Distribution of 11C-MK-3168 in Brain at Day 1, Dose Dependent Occupancy of Fatty Acid Amide Hydrolase (FAAH) After Single Dose of JNJ-42165279 up to 5 weeks and 1 more. Started Feb 2014; status: completed.

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Drugs

JNJ-42165279
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Conditions

Social Anxiety Disorder (SAD)major depressive disorder (MDD)

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