Trial intelligence / Profile preview

ALCHEMIST: Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial

NCT02194738Active, not recruiting

Sponsor
National Cancer Institute
Start
Sep 2014
Primary completion
Dec 2025
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes, Small Molecules
Countries
3
01

Overview

Randomised, open-label trial of erlotinib, crizotinib, nivolumab and pembrolizumab in non-small cell lung cancer (NSCLC) (11 arms), sponsored by National Cancer Institute. Primary endpoints: Central and local clinical genotyping to facilitate accrual to the adjuvant Intergroup studies up to 4 years and Feasibility of research grade formalin-fixed, paraffin-embedded tissue collection for Center for Cancer Genomics (CCG) analysis up to 4 years. Started Sep 2014; status: active, not recruiting.

02

Drugs

erlotinibcrizotinibnivolumabpembrolizumab
03

Conditions

non-small cell lung cancer (NSCLC)

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