Trial intelligence / Profile preview

Surgery and Chemotherapy-Only for Wnt Positive Medulloblastoma

NCT02212574Phase 1Terminated

Sponsor
Sidney Kimmel Comprehensive Cancer Center
Start
Apr 2017
Primary completion
Nov 2018
Modality
Monoclonal Antibodies, DNA Intercalators/Alkylators, Lipid-based Nanoparticles
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of lomustine, vincristine sulfate liposome injection, Cisplatin micelle injection (HA132) and cyclophosphamide in medulloblastoma, sponsored by Sidney Kimmel Comprehensive Cancer Center. Primary endpoint: Progression Free Survival at 3 years. Started Apr 2017; status: terminated.

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Drugs

lomustinevincristine sulfate liposome injectionCisplatin micelle injection (HA132)cyclophosphamide
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Conditions

medulloblastoma

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