Trial intelligence / Profile preview

Safety and Tolerability of LCZ696 in PARADIGM-HF Patients

NCT02226120Phase 3Completed

Sponsor
Novartis
Start
Oct 2014
Primary completion
Dec 2017
Modality
Small Molecules
Countries
41
01

Overview

Phase 3, open-label, single-arm trial of sacubitril + valsartan in heart failure with reduced ejection fraction (HFrEF), sponsored by Novartis. Primary endpoint: Percentage of Participants With Treatment Emergent Adverse Events (AEs), Serious Adverse Events (SAEs) and Deaths at 30 months. Started Oct 2014; status: completed.

02

Drugs

sacubitril + valsartan
03

Conditions

heart failure with reduced ejection fraction (HFrEF)

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